Sometimes we know what God asks of us, but it isn't the easy thing to do.
We might know what God has asked of us because God has spoken to us through Scripture, Church teaching, opportunities that have presented themselves in our daily lives, or counsel we have received from others.
If we aren't careful. we could get caught up in rationalizing another path, talking us out of God's will for our lives.
It's important for us to remember that what is right is not always what is easy. This was true also for the early Church (and obviously for Jesus as well).
We should remain vigilant in prayer when we are at these crossroads. We may also wish to confirm our decided course of action through further study of Church teaching and through spiritual direction.
Eventually, though, there is a time for action. We should remember that God is with us and that we can do all things through him. (Phil. 4:13).